SLAIN1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLAIN1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,528 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SLAIN1-associated genes across cancer lineages are S100A2, CENPM, and EFS. Each is linked with SLAIN1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLAIN1-to-partner and partner-to-SLAIN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLAIN1 versus S100A2 in LSCC, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLAIN1→partner) and Y-score (partner→SLAIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCS100A2 →-2.243-0.570<.001<.00133
LUADCENPM →-0.652-0.522.008.00132
LUADEFS →+0.718+0.361.008.00932
LSCCJAG1 →-0.756-0.451.005.00332
LSCCCHRDL1 →+1.211+0.502<.001.00132
GBMPLLP →+0.953+0.372.001.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,528 associations by consensus.

SLAIN1 vs S100A2 — LSCC

Per-sample scatter of SLAIN1 vs S100A2 in LSCC (Pearson r = -0.42).

Explore this scatter interactively →

Exploration