SLAIN1

Across TCGA patient cohorts, SLAIN1 mutation is significantly associated with the RNA expression of many other genes, with 3,224 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLAIN1-associated genes across cancer lineages are ONECUT2, MTFP1, and TXNL4A. Each is linked with SLAIN1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLAIN1-to-partner and partner-to-SLAIN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ONECUT2 grouped by SLAIN1-low versus SLAIN1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLAIN1→partner) and Y-score (partner→SLAIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ONECUT2 →	+0.452	+2.233	.002	<.001	3	3
UCEC	MTFP1 →	+0.454	+1.874	.005	.002	3	3
UCEC	TXNL4A →	+0.325	+2.627	.005	<.001	3	3
HNSC	GOLGA2P3Y →	+0.023	+4.655	<.001	.007	3	2
BRCA	MTCO1P57 →	+0.210	+5.646	<.001	.004	3	2
CESC	RNA5SP468 →	+0.328	+3.934	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,224 associations by consensus.

ONECUT2 by SLAIN1 expression — UCEC

Explore this box plot interactively →