SKP2

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SKP2 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,397 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SKP2-associated proteins across cancer lineages are CDK1, TOP2A, and TRIP13. Each is linked with SKP2 in more than 8 cancer types. Because this analysis shows association rather than direction, both SKP2-to-partner and partner-to-SKP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SKP2 versus CDK1 in LSCC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SKP2→partner) and Y-score (partner→SKP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCCDK1 →+0.678+0.814<.001<.00139
LSCCTOP2A →+0.982+0.812<.001<.00139
LSCCTRIP13 →+0.705+0.803<.001<.00139
GBMMSH6 →+0.536+0.438<.001<.00139
OVNCAPG_S674 →+0.893+0.690.007<.00139
HNSCPDS5A_T1208 →+0.624+0.879<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 19,397 associations by consensus.

SKP2 vs CDK1 — LSCC

Per-sample scatter of SKP2 vs CDK1 in LSCC (Pearson r = 0.45).

Explore this scatter interactively →

Exploration