Across TCGA cell cohorts, SKOR2 mutation is significantly associated with the mutation status of many other genes, with 2,790 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SKOR2-associated genes across cancer lineages are PHKB, CNNM1, and CPEB2. Each is linked with SKOR2 in more than 3 cancer types. Because this analysis shows association rather than direction, both SKOR2-to-partner and partner-to-SKOR2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SKOR2→partner) and Y-score (partner→SKOR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	PHKB →	+3.053	+3.718	.006	.006	1	4
LARGE_INTESTINE	CNNM1 →	+1.860	+2.263	.002	.002	1	4
LARGE_INTESTINE	CPEB2 →	+2.445	+2.248	.003	.003	1	4
LARGE_INTESTINE	ATXN7 →	+2.182	+2.099	.005	.005	1	4
OESOPHAGUS	PEG3 →	+2.722	+3.906	.004	.004	1	3
LUNG_NSCLC_LUAD	SERPINA9 →	+3.478	+3.303	.006	.006	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,790 associations by consensus.

Exploration

SKOR2 survival (RNA) · tumor vs normal (RNA) · all SKOR2 data types