Across TCGA patient cohorts, SKOR1 mutation is significantly associated with the RNA expression of many other genes, with 3,574 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SKOR1-associated genes across cancer lineages are MIR194-1, CYFIP1, and TAF9. Each is linked with SKOR1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SKOR1-to-partner and partner-to-SKOR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SKOR1→partner) and Y-score (partner→SKOR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR194-1 →	+0.502	+3.391	<.001	.003	3	3
UCEC	CYFIP1 →	+0.389	+1.740	.002	.002	3	2
UCEC	TAF9 →	+0.567	+1.736	<.001	<.001	3	2
UCEC	CCL4 →	+0.763	+1.758	<.001	<.001	3	2
UCEC	TUBGCP5 →	+0.402	+1.769	<.001	<.001	3	2
SKCM	EIF4A1P3 →	+0.286	+3.603	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,574 associations by consensus.

Exploration

SKOR1 survival (RNA) · tumor vs normal (RNA) · all SKOR1 data types