Across TCGA cell cohorts, SKOR1 mutation is significantly associated with the RNA expression of many other genes, with 428 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SKOR1-associated genes across cancer lineages are CABP5, AKAP4, and KRT84. Each is linked with SKOR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SKOR1-to-partner and partner-to-SKOR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SKOR1→partner) and Y-score (partner→SKOR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	CABP5 →	+0.016	+4.867	<.001	.009	3	2
LUNG_NSCLC_LUAD	AKAP4 →	+0.010	+3.544	.001	.009	3	1
LUNG_NSCLC_LUAD	KRT84 →	+0.032	+3.760	.004	.008	3	1
LUNG_NSCLC_LUAD	KRT28 →	+0.005	+3.544	<.001	.009	3	1
LUNG_NSCLC_LUAD	TEX33 →	+0.022	+4.681	<.001	.003	3	1
LUNG_NSCLC_LUAD	OR4C12 →	+0.011	+4.078	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 428 associations by consensus.

Exploration

SKOR1 survival (RNA) · tumor vs normal (RNA) · all SKOR1 data types