Across TCGA cell cohorts, SKOR1 mutation is significantly associated with the mutation status of many other genes, with 6,526 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SKOR1-associated genes across cancer lineages are NUP98, ZMIZ1, and ZZEF1. Each is linked with SKOR1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SKOR1-to-partner and partner-to-SKOR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SKOR1→partner) and Y-score (partner→SKOR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	NUP98 →	+3.632	+3.930	.003	.003	1	6
BLOOD_Leukemia	ZMIZ1 →	+3.078	+3.847	<.001	<.001	1	5
LUNG_NSCLC_LUAD	ZZEF1 →	+5.000	+4.187	.008	.008	1	5
BLOOD_Leukemia	CELSR3 →	+2.222	+3.706	<.001	<.001	1	5
LUNG_NSCLC_LUAD	GRK2 →	+5.000	+4.187	.008	.008	1	5
BLOOD_Leukemia	BRPF1 →	+3.662	+3.285	.004	.004	1	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,526 associations by consensus.

Exploration

SKOR1 survival (RNA) · tumor vs normal (RNA) · all SKOR1 data types