SKIV2L

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SKIV2L mutation is significantly associated with the total protein of many other genes, with 49 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SKIV2L-associated genes across cancer lineages are c-Met_pY1235, Lck, and MIG-6. Each is linked with SKIV2L in more than 2 cancer types. Because this analysis shows association rather than direction, both SKIV2L-to-partner and partner-to-SKIV2L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SKIV2L→partner) and Y-score (partner→SKIV2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECc-Met_pY1235 →+0.062+1.662.017.01133
SKCMLck →+0.304+1.874.036.04933
SKCMMIG-6 →+0.188+1.602.006.04233
UCECeEF2 →+0.284+1.874.024.04932
UCECeIF4E →+0.204+2.874.006<.00132
UCECERK2 →+0.239+2.906<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

Exploration