Across TCGA cell cohorts, SKIV2L mutation is significantly associated with the RNA expression of many other genes, with 151 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SKIV2L-associated genes across cancer lineages are MAGEB4, KRTAP19-8, and NPVF. Each is linked with SKIV2L in more than 2 cancer types. Because this analysis shows association rather than direction, both SKIV2L-to-partner and partner-to-SKIV2L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SKIV2L→partner) and Y-score (partner→SKIV2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MAGEB4 →	+0.008	+2.830	.001	.004	3	3
SKIN	KRTAP19-8 →	+0.164	+4.415	<.001	.007	3	2
STOMACH	NPVF →	+0.015	+4.285	<.001	.007	3	1
BREAST	OR56A4 →	+0.048	+4.421	<.001	.004	3	1
BREAST	KRTAP8-1 →	+0.112	+4.781	<.001	.003	3	1
BLOOD_Leukemia	CRYBB3 →	+0.069	+2.982	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 151 associations by consensus.

Exploration

SKIV2L survival (RNA) · tumor vs normal (RNA) · all SKIV2L data types