SKIL

Across TCGA patient cohorts, SKIL RNA expression is significantly associated with the protein abundance of many other proteins, with 9,599 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SKIL-associated proteins across cancer lineages are CCN2, SULF1, and P3H4. Each is linked with SKIL in more than 6 cancer types. Because this analysis shows association rather than direction, both SKIL-to-partner and partner-to-SKIL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SKIL versus CCN2 in OV, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SKIL→partner) and Y-score (partner→SKIL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CCN2 →	+0.635	+0.770	<.001	<.001	3	7
CCRCC	SULF1 →	+0.892	+0.500	<.001	<.001	3	6
OV	P3H4 →	+0.528	+0.636	<.001	<.001	3	6
CCRCC	PCOLCE →	+0.828	+0.537	<.001	<.001	3	6
PDAC	ISLR →	+0.746	+0.442	<.001	.001	3	6
CCRCC	DBN1 →	+0.392	+0.495	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,599 associations by consensus.

SKIL vs CCN2 — OV

Explore this scatter interactively →