SKAP1

Across TCGA patient cohorts, SKAP1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,869 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SKAP1-associated genes across cancer lineages are SH2D1A, PDCD1, and PAX5. Each is linked with SKAP1 in more than 7 cancer types. Because this analysis shows association rather than direction, both SKAP1-to-partner and partner-to-SKAP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SKAP1 versus SH2D1A in OV, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SKAP1→partner) and Y-score (partner→SKAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SH2D1A →	+1.662	+1.130	.002	.006	3	8
CCRCC	PDCD1 →	+1.284	+0.641	<.001	<.001	3	8
HNSC	PAX5 →	+0.828	+0.661	.004	.002	3	8
OV	TRBV6-6 →	+1.397	+0.793	<.001	.003	3	8
OV	TRAV12-3 →	+1.337	+1.152	.002	.006	3	8
CCRCC	TRAJ34 →	+1.390	+0.522	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,869 associations by consensus.

SKAP1 vs SH2D1A — OV

Explore this scatter interactively →