SKAP1

Across TCGA cell cohorts, SKAP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,387 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SKAP1-associated GO terms across cancer lineages are Protein localization to membrane, Protein localization to plasma membrane, and Extracellular vesicle biogenesis. Each is linked with SKAP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both SKAP1-to-partner and partner-to-SKAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to membrane grouped by SKAP1-low versus SKAP1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SKAP1→partner) and Y-score (partner→SKAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Protein localization to membrane →	+0.043	+1.466	<.001	.003	3	7
LARGE_INTESTINE	Protein localization to plasma membrane →	+0.043	+1.553	.001	<.001	3	7
KIDNEY	Extracellular vesicle biogenesis →	+0.117	+1.907	.001	.001	3	7
OVARY	Positive regulation of CD4-positive, alpha-beta T cell activation →	+0.087	+1.490	.005	.003	3	7
LARGE_INTESTINE	Regulation of ATF6-mediated unfolded protein response →	+0.135	+1.670	<.001	.001	3	6
LARGE_INTESTINE	Protein localization to cell periphery →	+0.052	+1.575	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,387 associations by consensus.

Protein localization to membrane by SKAP1 expression — LARGE_INTESTINE

Explore this box plot interactively →