SKA3

Across TCGA cell cohorts, SKA3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,029 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SKA3-associated GO terms across cancer lineages are Mitotic nuclear division, Positive regulation of mitotic sister chromatid separation, and Positive regulation of metaphase/anaphase transition of cell cycle. Each is linked with SKA3 in more than 19 cancer types. Because this analysis shows association rather than direction, both SKA3-to-partner and partner-to-SKA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic nuclear division grouped by SKA3-low versus SKA3-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SKA3→partner) and Y-score (partner→SKA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Mitotic nuclear division →	+0.097	+1.213	<.001	<.001	3	20
BONE	Positive regulation of mitotic sister chromatid separation →	+0.178	+1.603	.002	<.001	3	20
URINARY_TRACT	Positive regulation of metaphase/anaphase transition of cell cycle →	+0.193	+1.504	<.001	<.001	3	20
OESOPHAGUS	Nuclear division →	+0.111	+1.241	.001	.004	3	20
BONE	Mitotic sister chromatid segregation →	+0.116	+1.273	.003	.009	3	20
OESOPHAGUS	Regulation of mitotic nuclear division →	+0.152	+1.414	.002	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,029 associations by consensus.

Mitotic nuclear division by SKA3 expression — BREAST

Explore this box plot interactively →