Across TCGA patient cohorts, SIVA1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,776 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SIVA1-associated proteins across cancer lineages are MTA1, SUPT16H, and BAG5. Each is linked with SIVA1 in more than 7 cancer types. Because this analysis shows association rather than direction, both SIVA1-to-partner and partner-to-SIVA1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SIVA1→partner) and Y-score (partner→SIVA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MTA1 →	+0.559	+0.420	<.001	<.001	3	8
LSCC	SUPT16H →	+0.383	+0.469	<.001	<.001	3	7
GBM	BAG5 →	+0.362	+0.389	<.001	<.001	3	7
LSCC	UBR7 →	+0.396	+0.602	<.001	<.001	3	7
LSCC	VRK1 →	+0.515	+0.511	<.001	<.001	3	7
GBM	RCOR1 →	+0.533	+0.463	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,776 associations by consensus.

Exploration

SIVA1 survival (RNA) · tumor vs normal (RNA) · all SIVA1 data types