SINHCAFP1

Across TCGA pan-cancer cohorts, SINHCAFP1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated SINHCAFP1 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher SINHCAFP1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SINHCAFP1 expression acts as an unfavorable survival marker, although some lineages such as CHOL and UCS show a favorable association.

LIHC, CHOL, and OV are the cancer types where SINHCAFP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	DFS	Tertile	All	0.272	0.471	<.001	84	view →
CHOL	DFS	Tertile	All	0.877	0.133	<.001	60	view →
OV	OS	Median	All	0.617	0.746	<.001	40	view →
BLCA	DFS	Quartile	II,III,IV	0.507	0.688	.003	30	view →
PAAD	OS	Tertile	II,III,IV	0.263	0.605	.015	29	view →
UCS	OS	Tertile	IV	0.883	0.294	.024	24	view →
PRAD	DFS	Median	All	0.961	0.905	<.001	14	view →
ACC	DFS	Tertile	II,III,IV	0.472	0.792	.023	10	view →
SKCM	OS	Quartile	II,III,IV	0.496	0.158	.004	8	view →
GBM	DFS	Tertile	All	0.417	0.224	.032	8	view →
READ	OS	Tertile	IV	0.517	1.000	.020	8	view →
LGG	DFS	Quartile	All	0.878	0.765	.014	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

SINHCAFP1–LIHC (DFS)

Open the LIHC breakdown →