SINHCAFP1

Across TCGA pan-cancer cohorts, SINHCAFP1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of SINHCAFP1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where SINHCAFP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SINHCAFP1 is over-expressed in tumor, although a few such as KIRC and THCA show the opposite, repressed pattern.

COAD, KIRC, and HNSC are the cancer types where SINHCAFP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SINHCAFP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	+0.725	<.001	11	view →
KIRC	All	III,IV	−0.187	<.001	11	view →
HNSC	Male	All	+0.269	<.001	8	view →
STAD	All	II,III,IV	+0.427	.009	6	view →
LUAD	All	All	+0.368	<.001	6	view →
LUSC	All	All	+0.244	<.001	5	view →
BLCA	All	III,IV	+0.215	.006	4	view →
THCA	Male	II,III,IV	−0.132	.016	3	view →
READ	All	All	+0.591	.005	2	view →
ESCA	Female	All	+0.466	.011	1	view →
CHOL	All	All	+0.208	.025	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

SINHCAFP1–COAD

Open the COAD breakdown →