SINHCAF

Across TCGA patient cohorts, SINHCAF protein abundance is significantly associated with the RNA expression of many other genes, with 16,923 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SINHCAF-associated genes across cancer lineages are MRPL51, CCDC77, and CCNB1IP1. Each is linked with SINHCAF in more than 5 cancer types. Because this analysis shows association rather than direction, both SINHCAF-to-partner and partner-to-SINHCAF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SINHCAF versus MRPL51 in HNSC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SINHCAF→partner) and Y-score (partner→SINHCAF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MRPL51 →	+0.824	+0.512	.002	.002	3	6
HNSC	CCDC77 →	+1.017	+0.691	.002	<.001	3	6
LSCC	CCNB1IP1 →	+0.695	+0.555	<.001	<.001	3	5
HNSC	NCAPD2 →	+1.464	+0.828	<.001	<.001	3	5
UCEC	TTK →	+1.313	+0.552	<.001	<.001	3	5
HNSC	NCAPH →	+0.744	+0.516	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,923 associations by consensus.

SINHCAF vs MRPL51 — HNSC

Explore this scatter interactively →