SINHCAF

Across TCGA cell cohorts, SINHCAF RNA expression is significantly associated with the go_rna of many other GO terms, with 5,398 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SINHCAF-associated GO terms across cancer lineages are Nuclear pore organization, Positive regulation of cytoplasmic mRNA processing body assembly, and Positive regulation of type B pancreatic cell development. Each is linked with SINHCAF in more than 11 cancer types. Because this analysis shows association rather than direction, both SINHCAF-to-partner and partner-to-SINHCAF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear pore organization grouped by SINHCAF-low versus SINHCAF-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SINHCAF→partner) and Y-score (partner→SINHCAF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nuclear pore organization →	+0.148	+1.450	.001	.001	3	12
LUNG_NSCLC_LUSC	Positive regulation of cytoplasmic mRNA processing body assembly →	+0.095	+1.422	<.001	<.001	3	12
BLOOD_Myeloma	Positive regulation of type B pancreatic cell development →	-0.209	-0.998	<.001	<.001	3	12
OVARY	Heterochromatin formation →	+0.061	+0.984	<.001	<.001	3	12
BONE	Epigenetic regulation of gene expression →	+0.078	+1.708	.006	.003	3	12
BONE	Carbohydrate derivative catabolic process →	-0.090	-1.747	.001	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,398 associations by consensus.

Nuclear pore organization by SINHCAF expression — BONE

Explore this box plot interactively →