Across TCGA patient cohorts, SIM1-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,092 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SIM1-AS1-associated GO terms across cancer lineages are Cellular response to radiation, Negative regulation of autophagy, and Negative regulation of double-strand break repair via homologous recombination. Each is linked with SIM1-AS1 in more than 10 cancer types. Because this analysis shows association rather than direction, both SIM1-AS1-to-partner and partner-to-SIM1-AS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SIM1-AS1→partner) and Y-score (partner→SIM1-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Cellular response to radiation →	+0.155	+0.043	<.001	.006	2	11
ESCA	Negative regulation of autophagy →	+0.131	+0.035	<.001	.001	2	11
STAD	Negative regulation of double-strand break repair via homologous recombination →	+0.096	+0.074	<.001	<.001	3	9
STAD	Protein folding →	+0.123	+0.083	<.001	<.001	3	9
ESCA	Golgi organization →	+0.138	+0.036	<.001	.004	2	10
ESCA	Nuclear-transcribed mRNA catabolic process →	+0.173	+0.027	<.001	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,092 associations by consensus.

Exploration

SIM1-AS1 survival (RNA) · tumor vs normal (RNA) · all SIM1-AS1 data types