SIK1B

Across TCGA patient cohorts, SIK1B RNA expression is significantly associated with the protein abundance of many other proteins, with 8,079 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SIK1B-associated proteins across cancer lineages are CPN2, SLC15A4, and FLNA_S2339. Each is linked with SIK1B in more than 4 cancer types. Because this analysis shows association rather than direction, both SIK1B-to-partner and partner-to-SIK1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SIK1B versus CPN2 in CCRCC, with a Pearson correlation of 0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SIK1B→partner) and Y-score (partner→SIK1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	CPN2 →	+0.564	+0.685	.001	.008	3	4
GBM	SLC15A4 →	+0.348	+0.536	.007	.002	3	4
GBM	FLNA_S2339 →	+0.809	+0.906	<.001	<.001	3	4
CCRCC	PROC →	+0.486	+0.773	.002	.001	2	4
OV	PROS1 →	+0.610	+0.762	.007	.006	1	5
UCEC	SPP2_S96 →	+0.656	+0.780	.008	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,079 associations by consensus.

SIK1B vs CPN2 — CCRCC

Explore this scatter interactively →