SIGLEC31P

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, SIGLEC31P RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of SIGLEC31P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where SIGLEC31P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SIGLEC31P is over-expressed in tumor.

KIRP are the cancer types where SIGLEC31P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SIGLEC31P RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KIRPFemaleAll+0.088.0231view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

SIGLEC31P–KIRP

Tumor-vs-normal expression box plot for SIGLEC31P RNA in KIRP.

Open the KIRP breakdown →

Exploration