SIGLEC27P

Across TCGA patient cohorts, SIGLEC27P RNA expression is significantly associated with the go_rna of many other GO terms, with 5,572 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SIGLEC27P-associated GO terms across cancer lineages are Response to toxic substance, Pyrimidine-containing compound metabolic process, and rRNA modification. Each is linked with SIGLEC27P in more than 5 cancer types. Because this analysis shows association rather than direction, both SIGLEC27P-to-partner and partner-to-SIGLEC27P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to toxic substance grouped by SIGLEC27P-low versus SIGLEC27P-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SIGLEC27P→partner) and Y-score (partner→SIGLEC27P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Response to toxic substance →	+0.081	+0.084	<.001	<.001	3	6
ESCA	Pyrimidine-containing compound metabolic process →	+0.116	+0.020	<.001	.005	2	6
STAD	rRNA modification →	+0.106	+0.042	<.001	<.001	3	5
STAD	Peptidyl-arginine modification →	+0.054	+0.047	<.001	<.001	3	5
ESCA	Dicarboxylic acid metabolic process →	+0.125	+0.019	<.001	.006	3	5
STAD	Negative regulation of growth →	+0.078	+0.045	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,572 associations by consensus.

Response to toxic substance by SIGLEC27P expression — STAD

Explore this box plot interactively →