SIGLEC18P

Across TCGA patient cohorts, SIGLEC18P RNA expression is significantly associated with the protein abundance of many other proteins, with 13,307 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SIGLEC18P-associated proteins across cancer lineages are DPYD, HCK, and LSP1. Each is linked with SIGLEC18P in more than 7 cancer types. Because this analysis shows association rather than direction, both SIGLEC18P-to-partner and partner-to-SIGLEC18P results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SIGLEC18P versus DPYD in GBM, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SIGLEC18P→partner) and Y-score (partner→SIGLEC18P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DPYD →	+0.620	+0.381	<.001	<.001	3	8
GBM	HCK →	+0.623	+0.557	<.001	<.001	3	7
GBM	LSP1 →	+0.657	+0.630	<.001	<.001	3	6
GBM	MSN →	+0.406	+0.386	<.001	.003	3	6
GBM	MYO1F →	+0.598	+0.656	<.001	<.001	3	6
LSCC	ELMO2 →	+0.231	+0.239	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,307 associations by consensus.

SIGLEC18P vs DPYD — GBM

Explore this scatter interactively →