SIGLEC10-AS1

Across TCGA patient cohorts, SIGLEC10-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,042 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible SIGLEC10-AS1-associated GO terms across cancer lineages are Mitotic sister chromatid separation, Spindle organization, and Regulation of chromosome organization. Each is linked with SIGLEC10-AS1 in more than 30 cancer types. Because this analysis shows association rather than direction, both SIGLEC10-AS1-to-partner and partner-to-SIGLEC10-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic sister chromatid separation grouped by SIGLEC10-AS1-low versus SIGLEC10-AS1-high in THYM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SIGLEC10-AS1→partner) and Y-score (partner→SIGLEC10-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Mitotic sister chromatid separation →	+0.082	+0.374	<.001	<.001	3	30
ESCA	Spindle organization →	+0.055	+0.182	.001	.002	2	31
THYM	Regulation of chromosome organization →	+0.060	+0.402	<.001	<.001	3	30
THYM	Chromosome separation →	+0.086	+0.408	<.001	<.001	3	29
STAD	Regulation of nuclear division →	+0.065	+0.253	<.001	<.001	3	29
ESCA	Positive regulation of cell cycle process →	+0.055	+0.245	<.001	<.001	2	30

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,042 associations by consensus.

Mitotic sister chromatid separation by SIGLEC10-AS1 expression — THYM

Explore this box plot interactively →