SIDT1

Across TCGA patient cohorts, SIDT1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,518 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SIDT1-associated genes across cancer lineages are SIDT1-AS1, MIR4446, and CAPN13. Each is linked with SIDT1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SIDT1-to-partner and partner-to-SIDT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SIDT1 versus SIDT1-AS1 in UCEC, with a Pearson correlation of 0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SIDT1→partner) and Y-score (partner→SIDT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SIDT1-AS1 →	+1.731	+1.032	<.001	<.001	3	4
UCEC	MIR4446 →	+2.212	+0.897	<.001	<.001	3	4
BRCA	CAPN13 →	+1.813	+0.629	<.001	<.001	3	3
LUAD	RTN4RL1 →	+1.091	+0.793	.009	.006	3	3
BRCA	BTG3 →	-1.171	-0.777	<.001	<.001	3	3
BRCA	SLC12A2 →	+0.963	+0.716	.009	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,518 associations by consensus.

SIDT1 vs SIDT1-AS1 — UCEC

Explore this scatter interactively →