SIDT1

Across TCGA cell cohorts, SIDT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,473 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SIDT1-associated GO terms across cancer lineages are Regulation of glutamate uptake involved in transmission of nerve impulse, Positive regulation of endoplasmic reticulum unfolded protein response, and Establishment or maintenance of microtubule cytoskeleton polarity. Each is linked with SIDT1 in more than 9 cancer types. Because this analysis shows association rather than direction, both SIDT1-to-partner and partner-to-SIDT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of glutamate uptake involved in transmission of nerve impulse grouped by SIDT1-low versus SIDT1-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SIDT1→partner) and Y-score (partner→SIDT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Regulation of glutamate uptake involved in transmission of nerve impulse →	-0.200	-0.807	.004	.001	3	10
URINARY_TRACT	Positive regulation of endoplasmic reticulum unfolded protein response →	+0.120	+2.253	<.001	<.001	3	8
URINARY_TRACT	Establishment or maintenance of microtubule cytoskeleton polarity →	-0.196	-2.117	<.001	.001	3	8
BREAST	Hypotonic salinity response →	+1.179	+2.244	<.001	<.001	3	8
BREAST	Cellular hypotonic salinity response →	+1.179	+2.244	<.001	<.001	3	8
OESOPHAGUS	Positive regulation of IRE1-mediated unfolded protein response →	+0.170	+1.132	.005	.008	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,473 associations by consensus.

Regulation of glutamate uptake involved in transmission of nerve impulse by SIDT1 expression — BLOOD_Leukemia

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