SHROOM4

Across TCGA cell cohorts, SHROOM4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,684 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SHROOM4-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Ribonucleoside diphosphate metabolic process, and Regulation of intracellular transport. Each is linked with SHROOM4 in more than 7 cancer types. Because this analysis shows association rather than direction, both SHROOM4-to-partner and partner-to-SHROOM4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by SHROOM4-low versus SHROOM4-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SHROOM4→partner) and Y-score (partner→SHROOM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of myoblast fusion →	+0.127	+0.860	.001	.003	3	8
BREAST	Ribonucleoside diphosphate metabolic process →	+0.077	+0.452	<.001	<.001	3	8
BREAST	Regulation of intracellular transport →	+0.051	+0.419	.001	.005	3	8
OVARY	Protein stabilization →	+0.058	+0.712	<.001	.006	2	8
STOMACH	Vacuolar transport →	+0.081	+0.862	<.001	.003	3	7
SOFT_TISSUE	Establishment of protein localization to endoplasmic reticulum →	+0.085	+0.704	<.001	.008	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,684 associations by consensus.

Negative regulation of myoblast fusion by SHROOM4 expression — STOMACH

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