SHKBP1

Across TCGA patient cohorts, SHKBP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,622 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SHKBP1-associated proteins across cancer lineages are ITGAM, PRPF40A_T346, and DDX39A. Each is linked with SHKBP1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SHKBP1-to-partner and partner-to-SHKBP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SHKBP1 versus ITGAM in CCRCC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SHKBP1→partner) and Y-score (partner→SHKBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ITGAM →	+0.610	+0.394	<.001	<.001	3	5
LUAD	PRPF40A_T346 →	+0.304	+0.341	.005	.008	3	4
UCEC	DDX39A →	+0.343	+0.643	.001	<.001	3	4
CCRCC	CEP68 →	-0.290	-0.276	<.001	<.001	3	4
OV	DOCK11 →	+0.397	+0.718	.004	<.001	3	4
GBM	GMIP →	+0.465	+0.442	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,622 associations by consensus.

SHKBP1 vs ITGAM — CCRCC

Explore this scatter interactively →