SHKBP1

Across TCGA patient cohorts, SHKBP1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,703 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SHKBP1-associated genes across cancer lineages are IL2RA, TMEM150B, and FTL. Each is linked with SHKBP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SHKBP1-to-partner and partner-to-SHKBP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SHKBP1 versus IL2RA in CCRCC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SHKBP1→partner) and Y-score (partner→SHKBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	IL2RA →	+1.024	+0.461	<.001	<.001	3	4
GBM	TMEM150B →	+0.904	+0.432	<.001	<.001	3	4
CCRCC	FTL →	+0.598	+0.405	.001	<.001	3	4
GBM	COBL →	-1.122	-0.377	.001	.005	3	3
GBM	CLEC2B →	+0.888	+0.334	.001	<.001	3	3
GBM	DSE →	+0.817	+0.406	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,703 associations by consensus.

SHKBP1 vs IL2RA — CCRCC

Explore this scatter interactively →