SHB

Across TCGA patient cohorts, SHB protein abundance is significantly associated with the RNA expression of many other genes, with 4,201 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SHB-associated genes across cancer lineages are RNU7-124P, FAM160A1, and UBE2R2. Each is linked with SHB in more than 3 cancer types. Because this analysis shows association rather than direction, both SHB-to-partner and partner-to-SHB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SHB versus RNU7-124P in LSCC, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SHB→partner) and Y-score (partner→SHB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RNU7-124P →	+1.607	+0.511	<.001	<.001	3	4
LSCC	FAM160A1 →	+0.632	+0.381	<.001	.002	3	3
LSCC	UBE2R2 →	+0.490	+0.340	<.001	.001	3	3
HNSC	DCAF10 →	+0.486	+0.474	.001	.008	3	3
LSCC	UBAP2 →	+0.575	+0.308	<.001	.002	3	3
LSCC	UBAP1 →	+0.718	+0.511	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,201 associations by consensus.

SHB vs RNU7-124P — LSCC

Explore this scatter interactively →