SHANK2-AS3

Across TCGA patient cohorts, SHANK2-AS3 RNA expression is significantly associated with the protein abundance of many other proteins, with 4,345 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SHANK2-AS3-associated proteins across cancer lineages are SHANK2, ZNRD2, and SHANK2_S96. Each is linked with SHANK2-AS3 in more than 4 cancer types. Because this analysis shows association rather than direction, both SHANK2-AS3-to-partner and partner-to-SHANK2-AS3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SHANK2-AS3 versus SHANK2 in HNSC, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SHANK2-AS3→partner) and Y-score (partner→SHANK2-AS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SHANK2 →	+0.945	+1.415	<.001	<.001	3	5
OV	ZNRD2 →	+0.417	+0.031	.002	.008	3	2
HNSC	SHANK2_S96 →	+1.263	+0.976	<.001	.007	1	4
LUAD	MINK1 →	-0.202	-0.325	<.001	<.001	3	2
LUAD	NUMA1 →	+0.208	+0.550	.002	<.001	3	2
HNSC	FRMD4B →	-0.457	-1.008	.005	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,345 associations by consensus.

SHANK2-AS3 vs SHANK2 — HNSC

Explore this scatter interactively →