SHANK2-AS3

Across TCGA patient cohorts, SHANK2-AS3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,211 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SHANK2-AS3-associated GO terms across cancer lineages are Regulation of microtubule-based process, Peptidyl-lysine modification, and Peptidyl-lysine acetylation. Each is linked with SHANK2-AS3 in more than 12 cancer types. Because this analysis shows association rather than direction, both SHANK2-AS3-to-partner and partner-to-SHANK2-AS3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of microtubule-based process grouped by SHANK2-AS3-low versus SHANK2-AS3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SHANK2-AS3→partner) and Y-score (partner→SHANK2-AS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of microtubule-based process →	+0.037	+0.136	<.001	<.001	3	13
STAD	Peptidyl-lysine modification →	+0.048	+0.149	<.001	<.001	3	12
STAD	Peptidyl-lysine acetylation →	+0.049	+0.153	<.001	<.001	3	12
ESCA	Obsolete regulation of histone modification →	+0.061	+0.162	.002	<.001	3	12
STAD	Monosaccharide metabolic process →	+0.045	+0.147	<.001	<.001	3	12
STAD	Protein deacetylation →	+0.044	+0.140	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,211 associations by consensus.

Regulation of microtubule-based process by SHANK2-AS3 expression — STAD

Explore this box plot interactively →