SHANK2-AS2

Across TCGA patient cohorts, SHANK2-AS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,868 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SHANK2-AS2-associated proteins across cancer lineages are SHANK2, SHANK2_S1330, and SHANK2_S67. Each is linked with SHANK2-AS2 in more than 6 cancer types. Because this analysis shows association rather than direction, both SHANK2-AS2-to-partner and partner-to-SHANK2-AS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SHANK2-AS2 versus SHANK2 in HNSC, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SHANK2-AS2→partner) and Y-score (partner→SHANK2-AS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SHANK2 →	+0.666	+1.304	<.001	<.001	3	7
HNSC	SHANK2_S1330 →	+0.832	+1.082	<.001	<.001	3	4
HNSC	SHANK2_S67 →	+1.162	+1.301	<.001	<.001	3	4
GBM	SHANK2_S96 →	+1.297	+1.374	<.001	<.001	3	4
HNSC	SHANK2_S43 →	+1.359	+1.225	.002	.002	3	4
GBM	SHANK2_S452 →	+0.651	+1.517	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,868 associations by consensus.

SHANK2-AS2 vs SHANK2 — HNSC

Explore this scatter interactively →