Across TCGA patient cohorts, SHANK2-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,718 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SHANK2-AS1-associated proteins across cancer lineages are SHANK2, SHANK2_S43, and SHANK2_S452. Each is linked with SHANK2-AS1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SHANK2-AS1-to-partner and partner-to-SHANK2-AS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SHANK2-AS1→partner) and Y-score (partner→SHANK2-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SHANK2 →	+0.750	+1.020	<.001	<.001	3	6
HNSC	SHANK2_S43 →	+1.283	+0.976	<.001	.006	3	5
CCRCC	SHANK2_S452 →	+0.628	+0.615	<.001	.003	3	5
HNSC	SHANK2_S67 →	+1.583	+1.419	<.001	<.001	3	4
LSCC	SHANK2_S1330 →	+1.325	+0.828	<.001	.001	3	4
HNSC	SHANK2_S1071 →	+1.000	+1.077	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,718 associations by consensus.

Exploration

SHANK2-AS1 survival (RNA) · tumor vs normal (RNA) · all SHANK2-AS1 data types