SH3TC2

Across TCGA patient cohorts, SH3TC2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,079 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SH3TC2-associated proteins across cancer lineages are RBM6_S891, ZNF207, and TNS4_S350. Each is linked with SH3TC2 in more than 4 cancer types. Because this analysis shows association rather than direction, both SH3TC2-to-partner and partner-to-SH3TC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SH3TC2 versus RBM6_S891 in OV, with a Pearson correlation of -0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3TC2→partner) and Y-score (partner→SH3TC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RBM6_S891 →	-0.667	-0.117	<.001	<.001	3	4
GBM	ZNF207 →	-0.259	-0.842	<.001	.001	3	4
LUAD	TNS4_S350 →	+1.737	+0.203	<.001	.001	3	4
UCEC	PCDH1 →	+0.472	+0.357	<.001	.001	2	5
UCEC	SERPINB5 →	+1.419	+0.423	<.001	<.001	3	4
LUAD	ITGB4 →	+0.602	+0.208	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,079 associations by consensus.

SH3TC2 vs RBM6_S891 — OV

Explore this scatter interactively →