SH3TC1

Across TCGA patient cohorts, SH3TC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,448 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SH3TC1-associated proteins across cancer lineages are WDFY4, BTK, and FERMT3. Each is linked with SH3TC1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SH3TC1-to-partner and partner-to-SH3TC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SH3TC1 versus WDFY4 in GBM, with a Pearson correlation of 0.73.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3TC1→partner) and Y-score (partner→SH3TC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	WDFY4 →	+0.454	+0.959	<.001	<.001	3	6
OV	BTK →	+0.612	+0.669	.003	.002	3	6
GBM	FERMT3 →	+0.570	+0.962	<.001	<.001	3	6
GBM	FGD2 →	+0.440	+0.705	<.001	<.001	3	6
OV	NFKB1 →	+0.270	+0.635	<.001	.001	3	6
OV	ARHGAP45 →	+0.620	+0.759	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,448 associations by consensus.

SH3TC1 vs WDFY4 — GBM

Explore this scatter interactively →