SH3PXD2B

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SH3PXD2B RNA expression is significantly associated with the protein abundance of many other proteins, with 14,483 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SH3PXD2B-associated proteins across cancer lineages are MMP14, MMP2, and PLOD1. Each is linked with SH3PXD2B in more than 8 cancer types. Because this analysis shows association rather than direction, both SH3PXD2B-to-partner and partner-to-SH3PXD2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SH3PXD2B versus MMP14 in OV, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3PXD2B→partner) and Y-score (partner→SH3PXD2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVMMP14 →+0.509+1.043<.001<.00139
OVMMP2 →+0.825+1.150<.001<.00139
GBMPLOD1 →+0.491+0.462.002<.00139
CCRCCMXRA5 →+1.270+0.858<.001<.00138
CCRCCP3H4 →+0.587+0.806<.001<.00138
OVTIMP2 →+0.669+1.456<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,483 associations by consensus.

SH3PXD2B vs MMP14 — OV

Per-sample scatter of SH3PXD2B vs MMP14 in OV (Pearson r = 0.57).

Explore this scatter interactively →

Exploration