SH3PXD2B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SH3PXD2B protein abundance is significantly associated with the RNA expression of many other genes, with 13,317 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SH3PXD2B-associated genes across cancer lineages are SPARC, CALD1, and COL5A2. Each is linked with SH3PXD2B in more than 9 cancer types. Because this analysis shows association rather than direction, both SH3PXD2B-to-partner and partner-to-SH3PXD2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SH3PXD2B versus SPARC in OV, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3PXD2B→partner) and Y-score (partner→SH3PXD2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVSPARC →+1.683+0.530<.001<.001310
OVCALD1 →+1.076+0.456<.001<.001310
OVCOL5A2 →+2.008+0.474<.001<.001310
OVLGALS1 →+1.055+0.478<.001<.00139
OVPDGFRL →+1.212+0.436<.001<.00139
OVCCN4 →+1.328+0.432<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,317 associations by consensus.

SH3PXD2B vs SPARC — OV

Per-sample scatter of SH3PXD2B vs SPARC in OV (Pearson r = 0.67).

Explore this scatter interactively →

Exploration