SH3PXD2A

Across TCGA patient cohorts, SH3PXD2A protein abundance is significantly associated with the RNA expression of many other genes, with 11,641 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SH3PXD2A-associated genes across cancer lineages are UNC5B, FEZ1, and ADAMTS12. Each is linked with SH3PXD2A in more than 7 cancer types. Because this analysis shows association rather than direction, both SH3PXD2A-to-partner and partner-to-SH3PXD2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SH3PXD2A versus UNC5B in OV, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3PXD2A→partner) and Y-score (partner→SH3PXD2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	UNC5B →	+1.205	+0.710	<.001	<.001	3	8
LSCC	FEZ1 →	+0.812	+0.335	<.001	.001	3	8
OV	ADAMTS12 →	+1.442	+0.557	<.001	<.001	3	8
OV	MYL9 →	+1.241	+0.644	<.001	<.001	3	7
OV	AEBP1 →	+1.962	+0.526	<.001	<.001	3	7
OV	LAMA4 →	+1.109	+0.578	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,641 associations by consensus.

SH3PXD2A vs UNC5B — OV

Explore this scatter interactively →