SH3PXD2A

Across TCGA cell cohorts, SH3PXD2A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,477 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SH3PXD2A-associated GO terms across cancer lineages are Viral translational termination-reinitiation, Negative regulation of myoblast fusion, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with SH3PXD2A in more than 9 cancer types. Because this analysis shows association rather than direction, both SH3PXD2A-to-partner and partner-to-SH3PXD2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral translational termination-reinitiation grouped by SH3PXD2A-low versus SH3PXD2A-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3PXD2A→partner) and Y-score (partner→SH3PXD2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Viral translational termination-reinitiation →	+0.079	+1.214	<.001	<.001	3	10
SOFT_TISSUE	Negative regulation of myoblast fusion →	+0.111	+2.101	<.001	<.001	3	10
SOFT_TISSUE	Negative regulation of syncytium formation by plasma membrane fusion →	+0.111	+2.139	<.001	<.001	3	10
BLOOD_Lymphoma	Regulation of syncytium formation by plasma membrane fusion →	+0.092	+1.491	<.001	<.001	3	9
SOFT_TISSUE	Regulation of canonical Wnt signaling pathway →	+0.053	+1.988	<.001	<.001	3	9
BLOOD_Lymphoma	Regulation of myoblast fusion →	+0.103	+1.392	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,477 associations by consensus.

Viral translational termination-reinitiation by SH3PXD2A expression — SKIN

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