SH3GL3

Across TCGA patient cohorts, SH3GL3 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,359 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SH3GL3-associated proteins across cancer lineages are SH3GL3_S265, AP3M1, and PARVA. Each is linked with SH3GL3 in more than 4 cancer types. Because this analysis shows association rather than direction, both SH3GL3-to-partner and partner-to-SH3GL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SH3GL3 versus SH3GL3_S265 in GBM, with a Pearson correlation of 0.74.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3GL3→partner) and Y-score (partner→SH3GL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SH3GL3_S265 →	+1.425	+2.217	<.001	<.001	3	5
OV	AP3M1 →	-0.239	-0.783	<.001	.002	3	4
LSCC	PARVA →	-0.305	-0.692	.001	<.001	3	4
GBM	PMM2 →	-0.293	-1.192	<.001	<.001	3	4
BRCA	POP1 →	+0.313	+0.413	<.001	<.001	3	4
GBM	NMI →	-0.543	-1.548	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,359 associations by consensus.

SH3GL3 vs SH3GL3_S265 — GBM

Explore this scatter interactively →