SH3BGRL

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SH3BGRL RNA expression is significantly associated with the protein abundance of many other proteins, with 16,396 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SH3BGRL-associated proteins across cancer lineages are LPP, CEBPZ, and MYLK. Each is linked with SH3BGRL in more than 5 cancer types. Because this analysis shows association rather than direction, both SH3BGRL-to-partner and partner-to-SH3BGRL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SH3BGRL versus LPP in COAD, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3BGRL→partner) and Y-score (partner→SH3BGRL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADLPP →+0.645+0.885<.001<.00136
BRCACEBPZ →-0.441-1.064<.001<.00136
COADMYLK →+0.643+0.691.002.00436
COADPDLIM7 →+0.678+0.760<.001.00136
LUADSNX18 →+0.301+0.576<.001<.00136
BRCACEBPZ_S629 →-0.518-0.669<.001.00536
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,396 associations by consensus.

SH3BGRL vs LPP — COAD

Per-sample scatter of SH3BGRL vs LPP in COAD (Pearson r = 0.42).

Explore this scatter interactively →

Exploration