SH2D6

Across TCGA patient cohorts, SH2D6 RNA expression is significantly associated with the RNA expression of many other genes, with 15,181 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible SH2D6-associated genes across cancer lineages are RAD51-AS1, DUSP28, and C2orf92. Each is linked with SH2D6 in more than 22 cancer types. Because this analysis shows association rather than direction, both SH2D6-to-partner and partner-to-SH2D6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SH2D6 versus RAD51-AS1 in SARC, with a Pearson correlation of 0.23.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SH2D6→partner) and Y-score (partner→SH2D6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SARC	RAD51-AS1 →	+1.105	+0.289	<.001	<.001	3	23
UCS	DUSP28 →	+0.714	+0.495	<.001	.003	3	22
TGCT	C2orf92 →	+0.882	+1.103	<.001	<.001	3	22
UCS	NFE2L1-DT →	+0.987	+0.479	<.001	.003	3	22
UCS	PCBP1-AS1 →	+0.553	+0.355	<.001	<.001	3	21
UCS	GTF2IP20 →	+0.999	+0.439	.003	.004	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,181 associations by consensus.

SH2D6 vs RAD51-AS1 — SARC

Explore this scatter interactively →