SH2D2A

Across TCGA patient cohorts, SH2D2A RNA expression is significantly associated with the RNA expression of many other genes, with 14,416 significant associations in total. THYM shows the largest number of these associations.

The most reproducible SH2D2A-associated genes across cancer lineages are CD247, CD6, and SLA2. Each is linked with SH2D2A in more than 32 cancer types. Because this analysis shows association rather than direction, both SH2D2A-to-partner and partner-to-SH2D2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SH2D2A versus CD247 in SKCM, with a Pearson correlation of 0.70.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SH2D2A→partner) and Y-score (partner→SH2D2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CD247 →	+1.781	+1.378	<.001	<.001	3	33
CHOL	CD6 →	+1.918	+1.457	<.001	.001	3	33
SKCM	SLA2 →	+1.735	+1.394	<.001	<.001	3	32
CHOL	CD2 →	+3.212	+2.020	<.001	<.001	3	32
CHOL	SIT1 →	+2.183	+1.464	<.001	.002	3	32
CHOL	CD27 →	+3.391	+1.927	<.001	<.001	3	32

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,416 associations by consensus.

SH2D2A vs CD247 — SKCM

Explore this scatter interactively →