SGSM3-AS1

Across TCGA pan-cancer cohorts, SGSM3-AS1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated SGSM3-AS1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher SGSM3-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SGSM3-AS1 expression acts as an unfavorable survival marker, although some lineages such as BLCA and READ show a favorable association.

MESO, BLCA, and KIRC are the cancer types where SGSM3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Quartile	II,III,IV	0.253	0.468	.007	47	view →
BLCA	OS	Median	II,III,IV	0.784	0.651	<.001	41	view →
KIRC	DFS	Median	II,III,IV	0.431	0.606	.003	35	view →
ESCA	OS	Tertile	All	0.322	1.000	.004	22	view →
ACC	OS	Tertile	III,IV	0.386	0.733	.004	17	view →
OV	DFS	Quartile	IV	0.374	0.660	.015	12	view →
THCA	DFS	Median	III,IV	0.511	0.822	.004	10	view →
HNSC	OS	Median	III,IV	0.442	0.645	.012	5	view →
READ	DFS	Quartile	II,III,IV	0.900	0.603	.016	5	view →
SKCM	OS	Median	All	0.389	0.275	.030	4	view →
KIRP	DFS	Median	All	0.371	0.708	.032	4	view →
COAD	DFS	Quartile	IV	0.198	0.540	.048	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

SGSM3-AS1–MESO (DFS)

Open the MESO breakdown →