SGSM3-AS1

Across TCGA pan-cancer cohorts, SGSM3-AS1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of SGSM3-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where SGSM3-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types SGSM3-AS1 is over-expressed in tumor, although a few such as UCEC and BRCA show the opposite, repressed pattern.

UCEC, BRCA, and THCA are the cancer types where SGSM3-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SGSM3-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	IV	−0.375	.014	4	view →
BRCA	All	IV	−0.345	.001	4	view →
THCA	All	All	−0.083	<.001	4	view →
PAAD	Male	All	+0.265	.017	2	view →
CHOL	All	All	+0.115	.018	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

SGSM3-AS1–UCEC

Open the UCEC breakdown →