SGSM2

Across TCGA patient cohorts, SGSM2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,279 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SGSM2-associated proteins across cancer lineages are METTL16, MLKL, and YWHAE. Each is linked with SGSM2 in more than 5 cancer types. Because this analysis shows association rather than direction, both SGSM2-to-partner and partner-to-SGSM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SGSM2 versus METTL16 in OV, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SGSM2→partner) and Y-score (partner→SGSM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	METTL16 →	+0.350	+0.668	<.001	<.001	3	6
GBM	MLKL →	-0.512	-0.370	<.001	<.001	3	5
BRCA	YWHAE →	+0.223	+0.616	<.001	<.001	3	5
BRCA	ERP44 →	-0.375	-0.651	<.001	.005	3	5
GBM	HTATIP2 →	-0.657	-0.444	<.001	<.001	3	5
BRCA	ISG20 →	-0.691	-0.571	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,279 associations by consensus.

SGSM2 vs METTL16 — OV

Explore this scatter interactively →