SGSM2

Across TCGA patient cohorts, SGSM2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,991 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SGSM2-associated genes across cancer lineages are PTPRD, RYR2, and EPHA6. Each is linked with SGSM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SGSM2-to-partner and partner-to-SGSM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SGSM2 versus PTPRD in UCEC, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SGSM2→partner) and Y-score (partner→SGSM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PTPRD →	+1.400	+0.383	.002	.002	3	2
GBM	RYR2 →	+1.252	+0.475	<.001	<.001	3	2
UCEC	EPHA6 →	+0.966	+0.353	.002	.007	3	2
BRCA	FBXL5 →	+0.886	+0.704	<.001	<.001	3	2
BRCA	SYTL2 →	+1.795	+0.836	.002	.002	3	2
LSCC	SELENOW →	+0.810	+0.626	.004	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,991 associations by consensus.

SGSM2 vs PTPRD — UCEC

Explore this scatter interactively →