SGSH

Across TCGA patient cohorts, SGSH protein abundance is significantly associated with the RNA expression of many other genes, with 8,984 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SGSH-associated genes across cancer lineages are CENPI, NCAPG, and LMNB1. Each is linked with SGSH in more than 4 cancer types. Because this analysis shows association rather than direction, both SGSH-to-partner and partner-to-SGSH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SGSH versus CENPI in UCEC, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SGSH→partner) and Y-score (partner→SGSH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CENPI →	-0.817	-0.385	<.001	<.001	3	5
BRCA	NCAPG →	-1.184	-0.449	<.001	<.001	3	5
UCEC	LMNB1 →	-0.667	-0.192	.003	.008	3	5
LUAD	ANLN →	-1.058	-0.459	<.001	<.001	3	5
UCEC	NCAPH →	-0.730	-0.347	.003	<.001	3	5
BRCA	STIL →	-0.730	-0.332	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,984 associations by consensus.

SGSH vs CENPI — UCEC

Explore this scatter interactively →