SGO2

Across TCGA patient cohorts, SGO2 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,512 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SGO2-associated proteins across cancer lineages are RIF1, RPL12_S38, and RRM2. Each is linked with SGO2 in more than 9 cancer types. Because this analysis shows association rather than direction, both SGO2-to-partner and partner-to-SGO2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SGO2 versus RIF1 in LSCC, with a Pearson correlation of 0.67.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SGO2→partner) and Y-score (partner→SGO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RIF1 →	+0.456	+0.770	<.001	<.001	3	10
LUAD	RPL12_S38 →	+1.262	+0.839	<.001	<.001	3	10
LUAD	RRM2 →	+0.907	+0.890	<.001	<.001	3	10
UCEC	RRM2_S20 →	+1.336	+0.713	<.001	<.001	3	10
UCEC	SMC2 →	+0.782	+0.939	<.001	<.001	3	10
UCEC	SMC4 →	+0.729	+0.951	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,512 associations by consensus.

SGO2 vs RIF1 — LSCC

Explore this scatter interactively →